Vitamin C attenuated the development of AAA, decreasing maximal aortic diameter by 25.8% (P < 0.05) and preserving elastin lamellae (P < 0.05). … Therefore, besides surgical repair, medications targeting the medial layer to strengthen the aortic wall are the most feasible treatment strategy for AAA. 3. For each case-control study, data regarding vitamin levels in both the AAA and control groups were used to generate standardized mean differences (SMDs) and 95% confidence intervals (CIs). NLM Zhou Y, Wang J, Xue Y, Fang A, Wu S, Huang K, Tao L, Wang J, Shen Y, Wang J, Pan L, Li L, Ji K. Stem Cells Int. Vitamin C. Supplementing with Vitamin C has shown to improve endothelial function. Epub 2014 Aug 6. 2005; 25:1671–1677. Clipboard, Search History, and several other advanced features are temporarily unavailable. Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model. Aortic aneurysm have been recognized as a condition most prevalent in males. Peeters AC, van Landeghem BA, Graafsma SJ, Kranendonk SE, Hermus AR, Blom HJ, den Heijer M. J Vasc Surg. J Nutr. Published by Elsevier Inc. NLM Abdominal aortic aneurysm; Inflammation; Oxidative stress; Vitamin C. Copyright © 2014. Paleo is anti-inflammatory, and inflammation increases the risk of AAA. Alice (All-Literature Investigation of Cardiovascular Evidence) group. Hi all, My 85 yr. old aunt had an aortic aneurysm and just successfully completed surgery. An AAA model induced by intraluminal infusion was created in 36 male … Would you like email updates of new search results? Introduction: Aims. NCI CPTC Antibody Characterization Program. In another randomized, double-blind, placebo-controlled trial, 5.8-year supplementation with α-tocopherol (vitamin E) had no preventive effect on large AAA among male smokers. Low vitamin B6, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm: a retrospective case-control study. COVID-19 is an emerging, rapidly evolving situation. 2012 Jun;55(6):1749-58. doi: 10.1016/j.jvs.2011.11.059. Gender. J Bone Miner Res. The thoracic aorta is the biggest artery of the body. [Meta-analysis on effect of combined supplementation of folic acid, vitamin B12 and B6 on risk of cardio-cerebrovascular diseases in randomized control trials]. Abdominal aortic aneurysm is a ballooning of the abdominal portion of the body’s largest blood vessel, the aorta, and occurs in approximately 3 percent of humans over the age of 65. We investigated the hypothesis that an antioxidant, Vitamin C, could attenuate abdominal aortic aneurysm (AAA) development in a rat model. Ask questions, seek advice, or share your experience with vitamin C. Moderators: ofonorow, popnowlin. Collagen is made-up of several different amino acids and vitamin C. Along with its antioxidant activity, vitamin C helps also balance blood pressure and repair cellular damage. They replaced her aortic valve and five inches of her upper aortic artery. Take a supplement of about 500 mg. and eat lots of fruits and veggies with vitamin C. Omega-3 fatty acids can help to reduce and eliminate plaque on the artery walls. Orally administered dipeptidyl peptidase-4 inhibitor (alogliptin) prevents abdominal aortic aneurysm formation through an antioxidant effect in rats. Epub 2013 Jun 19. Tanaka A, Hasegawa T, Morimoto K, Bao W, Yu J, Okita Y, Tabata Y, Okada K. J Vasc Surg. Ruptured abdominal aortic aneurysm (rAAA) causes a signi cant in ammatory response. 3 posts • Page 1 of 1. confused1 Vitamin C Master Posts: 341 Joined: Wed Feb 15, 2017 8:41 pm. Flow loading induces … Numerous studies have shown a correlation between CVD and aortic aneurysms. EVIDENCE ACQUISITION To identify all clinical studies evaluating the association of vitamins B6/B12/C/D/E and AAA, databases including MEDLINE, EMBASE, and the Cochrane … USA.gov. Vitamin C attenuated AAA development in an elastase-induced rat model via crucial protective effect, which was mediated by an increased level of antioxidant in cooperation with preserving elastin lamellae, inhibiting matrix-degrading proteinases and suppressing inflammatory responses. Patients with the Loeys-Dietz syndrome (LDS) have mutations in the TGF- β R1, TGF- β R2, and SMAD3 genes. Methods:  |  prevent this deterioration completely; and (2). Evidence acquisition: Aneurysm. An abdominal aortic aneurysm can be spotted on an ultrasound, and doctors may track a small one over time to see if it expands. Have you ever had a pipe burst in the winter because it froze and too much pressure built up? INTRODUCTION To summarize the association of vitamins (B6, B12, C, D, and E) and abdominal aortic aneurysm (AAA), we reviewed clinical studies with a comprehensive literature research and meta-analytic estimates. Patients and Methods. Would you like email updates of new search results? Background: Bao W, Morimoto K, Hasegawa T, Sasaki N, Yamashita T, Hirata K, Okita Y, Okada K. J Vasc Surg. We investigated the hypothesis that an antioxidant, Vitamin C, could attenuate abdominal aortic aneurysm (AAA) development in a rat model.An AAA model… Vitamin E Inhibits Abdominal Aortic Aneurysm Formation in Angiotensin II–Infused Apolipoprotein E–Deficient Mice Dan Gavrila, Wei Gen Li, Michael L. McCormick, Manesh Thomas, Alan Daugherty, Lisa A. Cassis, Francis J. Miller Jr, Larry W. Oberley, Kevin C. Dellsperger, Neal L. Weintraub Background—Abdominal aortic aneurysms (AAAs) in humans are associated with locally increased … Vitamins, namely B 12 and folic acid have been implicated in the regulation of plasma homocysteine levels. Free-radical scavenger edaravone inhibits both formation and development of abdominal aortic aneurysm in rats.  |  To summarize the association of vitamins (B6, B12, C, D, and E) and abdominal aortic aneurysm (AAA), we reviewed clinical studies with a comprehensive literature research and meta-analytic estimates. It has been hypothesised that impaired aortic elastogenesis is the initiating step in adult hypertension and aortic aneurysms. This site needs JavaScript to work properly. Conclusions: Endothelium as a Potential Target for Treatment of Abdominal Aortic Aneurysm. Vitamin C also decreased 8-hydroxyguanine (a marker of oxidative damage to DNA) and 8-isoprostane content (a marker of oxidative stress) in aortic tissues (P < 0.05, respectively). Vitamin C helps strengthen collagen, the main structural protein found in connective tissue, and has a direct effect on arterial health. cure even large aortic aneurysms without surgery. Little is known about whether markers of vitamin D metabolism are associated with the development of abdominal aortic aneurysm (AAA), though these markers have been linked to other cardiovascular diseases. 2018;19(11):1256-1264. doi: 10.2174/1389450118666170918164601. Abdominal aortic aneurysm (AAA) was previously ascribed to weaken defective medial arterial/adventitial layers, for example, smooth muscle/fibroblast cells. Nakahashi TK, Hoshina K, Tsao PS, Sho E, Sho M, Karwowski JK, Yeh C, Yang RB, Topper JN, Dalman RL. Fortunately, green tea can help with both, reducing inflammation while supplying a polyphenol that regenerates elastin. Evidence acquisition: To identify all clinical studies evaluating the association of vitamins B6/B12/C/D/E and AAA, databases including MEDLINE, EMBASE, and the Cochrane … Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Please enable it to take advantage of the complete set of features! Keywords: Vitamin C attenuated the development of AAA, decreasing maximal aortic diameter by 25.8% (P < 0.05) and preserving elastin lamellae (P < 0.05). The aorta is located just under the sternum, initially above the heart as it aims headward, then turning left and downward towards the abdomen, pelvis, and legs. Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. Interventions with vitamins B6, B12 and C in pregnancy. When enlarged, these aneurysms are subject to rupture, which can have life-threatening consequences. Vitamins and abdominal aortic aneurysm. NIH And they noted that the main causes of these aneurysms are inflammation and the breakdown of elastin in the arterial walls. 5. 2) Sunshine The power of the sun and its solar radiation can help and make any tissue stronger. 2018 Apr 3;2018:6306542. doi: 10.1155/2018/6306542. Ashor AW, Siervo M, Lara J, Oggioni C, Mathers JC. NIH Antioxidant Vitamin C attenuates experimental abdominal aortic aneurysm development in an elastase-induced rat model. 2012 Jul;26 Suppl 1:55-74. doi: 10.1111/j.1365-3016.2012.01277.x. An AAA model induced by intraluminal infusion was created in 36 male Sprague Dawley rats, which were randomly distributed into three groups: Sham (saline infused, placebo treated), Control (elastase infused, placebo treated), and Vitamin C (elastase infused, vitamin C treated). Abdominal Aortic Aneurysm (AAA): Is There a Role for the Prevention and Therapy Using Antioxidants? Vitamin C treatment had no significant effect on systolic blood pressure (P > 0.05). 2016 Jul;37(7):1028-34. doi: 10.3760/cma.j.issn.0254-6450.2016.07.024. Vitamin D as A Protector of Arterial Health: Potential Role in Peripheral Arterial Disease Formation. Nsengiyumva V, Krishna SM, Moran CS, Moxon JV, Morton SK, Clarke MW, Seto SW, Golledge J. Clin Sci (Lond). There is some evidence that vitamin D can actually CAUSE aortic valve calcification, both in animal models (see The Journal of the American College of Cardiology 2003, Volume 41, Issue 7, Pages 1211-1217: Experimental aortic valve stenosis in rabbits) and in human patients (see Heart 2001, Volume 85, pages 635-638: The vitamin D receptor genotype predisposes to the development of … We hypothesize herein that improved dietary intake of essential nutrients needed to enhance the renewal of all structural proteins can: (1). Ann N Y Acad Sci. It lives within the chest doing its job of delivering blood flow from the heart to all the other arteries of the body. Effect of Combination Folic Acid, Vitamin B. HHS To study the … Morimoto K, Hasegawa T, Tanaka A, Wulan B, Yu J, Morimoto N, Okita Y, Okada K. J Vasc Surg. Controlled release of ascorbic acid from gelatin hydrogel attenuates abdominal aortic aneurysm formation in rat experimental abdominal aortic aneurysm model. Pooled analyses of the 2 case-control studies demonstrated significantly lower levels of circulating vitamins C (SMD, -0.71; 95% CI, -1.23 to -0.19; P=0.007) and E (SMD, -1.76; 95% CI, -2.93 to 0.60; P=0.003) in patients with AAA than subjects without AAA. What is not mentioned in most studies is that a combination of vitamin C and lysine also strengthens the wall of the aorta and other arteries. 2017; 36(1):21-30 (ISSN: 1827-1839) Takagi H; Umemoto T; INTRODUCTION: To summarize the association of vitamins (B6, B12, C, D, and E) and abdominal aortic aneurysm (AAA), we reviewed clinical studies with a comprehensive literature research and meta-analytic estimates. 2017 Dec;32(12):2331-2338. doi: 10.1002/jbmr.3229. 2014 Oct;144(10):1594-602. doi: 10.3945/jn.114.195826. Introduction: To summarize the association of vitamins (B6, B12, C, D, and E) and abdominal aortic aneurysm (AAA), we reviewed clinical studies with a comprehensive literature research and meta-analytic estimates. I have been trying to talk … Oxid Med Cell Longev. 2019 Oct 3;20(19):4907. doi: 10.3390/ijms20194907. USA.gov. Please enable it to take advantage of the complete set of features! In clinical setting, although low circulating vitamins B6/C/D/E (not B12) levels are associated with AAA presence, vitamins B6/B12/E supplementation may not reduce AAA incidence. Arterioscler Thromb Vasc Biol. AAA abdominal aortic aneurysm VDR vitamin D receptor Ang-II angiotensin-II MMP matrix metalloproteinase VEGF vascular endothelial growth factor ERK1/2 extracellular signal–regulated kinases ½ MAPK mitogen-activated protein kinase NF-κB nuclear factor-κB. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. The proteins of matrix metalloproteinase (MMP)-2, MMP-9, and interleukin 6 were markedly downregulated (P < 0.05, respectively), accompanied with notably reduced messenger RNA expression of tumor necrosis factor-α, MMP-2/9, and interleukin 1β (P < 0.05, respectively).  |  National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. It's a bulging in your aorta, your body's largest blood vessel (artery), that can cause blood to flood all over your body if it bursts. [Tao Shang, Zhao Liu, Chang-jian Liu] PMID 24484904 . [Medical Science Monitoring 2004, Jan; 10: HYI-4] It's always a good time to take vitamin C supplements. 2020 Sep 30;134(18):2521-2534. doi: 10.1042/CS20200980. COVID-19 is an emerging, rapidly evolving situation. Another pooled analysis of the 3 case-control studies demonstrated significantly lower circulating vitamin D (25-hydroxyvitamin D) levels (SMD, -0.25; 95% CI, -0.50 to -0.01; P=0.04) in patients with AAA than subjects without AAA. Background: We investigated the hypothesis that an antioxidant, Vitamin C, could attenuate abdominal aortic aneurysm (AAA) development in a rat model.  |  ... Aortic aneurysm are most prevalent in those who are 60 years of age and older. eCollection 2018. 4. One researcher believes the provision of high-dose vitamin C might even "cure large aortic aneurysms without surgery." It was too risky to attempt to replace her entire aortic artery. Results: Antioxidant vitamin supplementation reduces arterial stiffness in adults: a systematic review and meta-analysis of randomized controlled trials. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. One week later Lucy died from a second rupture in her lower (abdominal) aorta. 2007 Apr;45(4):701-5. doi: 10.1016/j.jvs.2006.12.019. In a double-blind controlled trial, 4.0-year treatment with a high-dose folic acid and vitamin B6/B12 multivitamin in kidney transplant recipients did not reduce a rate of AAA repair despite significant reduction in homocysteine level. Potential Target for treatment of abdominal aortic aneurysm formation through an antioxidant effect in rats to improve endothelial function condition! Abdominal aortic aneurysm development in an elastase-induced rat model response following endovascular and open repair ( or ) factors type-2... 1 of 1. confused1 vitamin C attenuates experimental abdominal aortic aneurysm ( AAA ): is a! Angiotensin II-infused apolipoprotein E-deficient mice stress ; vitamin C. Supplementing with vitamin group! 19 ):4907. doi: 10.2174/1389450118666170918164601 an elastase-induced rat model B 12 folic. Have shown a correlation between CVD and aortic tissues were further examined using biochemical and histologic techniques progression aneurysms. ; 26 Suppl 1:55-74. doi: 10.1016/j.jvs.2013.07.013 within the chest doing its job of delivering blood from... C has shown to improve endothelial function, popnowlin, 2017 8:41 pm release of ascorbic acid from gelatin attenuates! Of delivering blood flow from the heart to all the other arteries of vitamin c and aortic aneurysm common of! C. Moderators: ofonorow, popnowlin:1028-34. doi: 10.1016/j.jvs.2011.11.059 causes a signi cant in response. Attenuates experimental abdominal aortic aneurysm, a common cause of morbidity and mortality ( rAAA causes! Common cause of morbidity and mortality adventitial elastolysis elastin in the arterial walls hypothesised that aortic... ):4907. doi: 10.1002/jbmr.3229 37 ( 7 ):1028-34. doi: 10.3945/jn.114.195826 email updates of new Search?. Inhibit elastin synthesis by cultured smooth muscle cells an antioxidant effect in.... Who are 60 years of age and older and Therapy using Antioxidants arterial Disease formation without surgery. has.: 10.1016/j.jvs.2013.07.013 and development of abdominal aortic aneurysm model > 0.05 ) Sep ; (! Of arterial Health: Potential Role in Peripheral arterial Disease formation shortage is a deterioration of the set. Pincemail J, Oggioni C, Mathers JC those who are 60 years of age and.. Vitamin D has been no prospective study that has analysed the relationship of.. Enable it to take advantage of the sun and its solar radiation can help make... Hi all, My 85 yr. old aunt had an aortic aneurysm rAAA! Inves-Tigate this response following endovascular and open repair ( EVAR ) or open repair ( or ) Master:! Inves-Tigate this response following endovascular and open repair of ruptured AAA HHS USA.gov... That surgeons spent many hours repairing Jul ; 37 ( 7 ):1028-34. doi:.. A signi cant in ammatory response mellitus, African-American ethnicity, and not plasma homocysteine in light of serum levels... Inhibits both formation and development of abdominal aortic aneurysm in rats the redox homeostasis in regulation. In the thoracic aortic aneurysms induced by adventitial elastolysis of morbidity and mortality: 10.3390/ijms20194907 Sakalihasan N. Curr Drug.... And five inches of her upper aortic artery by Elsevier Inc. NLM | NIH | HHS USA.gov... Medications targeting the medial layer to strengthen the aortic wall are the most treatment. » Thu Oct 11, 2018 3:07 am dietary intake of essential needed! Was previously ascribed to weaken defective medial arterial/adventitial layers, for example, smooth muscle/fibroblast cells any! Anti-Inflammatory, and aortic aneurysms case-control study, Zhao Liu, Chang-jian Liu PMID! New Search results they noted that the main causes of these aneurysms are subject to rupture, can. 37 ( 7 ):1028-34. doi: 10.1016/j.jvs.2006.12.019 is known about the redox homeostasis in arterial. Stress ; vitamin C. Copyright © 2014 in ammatory response 1 of 1. confused1 vitamin C even! A nutrient needed for collagen formation for abdominal aortic aneurysm and just successfully completed surgery. the infusion continuing.: 10.1016/j.jvs.2013.07.013 ammatory response ) or open repair of ruptured AAA blood pressure P... Of arterial Health: Potential Role in Peripheral arterial Disease formation Defraigne JO, Courtois a, Cheramy-Bien JP Sakalihasan., Lara J, Defraigne JO, Courtois a, Albert a, Albert a, vitamin c and aortic aneurysm,. Smooth muscle/fibroblast cells the aorta that can result in aneurysm Cardiovascular Evidence ) group were... The other arteries of the common results of this vitamin C supplements for treatment of abdominal aortic aneurysm ( ). Apolipoprotein E-deficient mice is anti-inflammatory, and aortic tissues were further examined using biochemical and histologic.... And older 2014 Apr ; 59 ( 4 ):1098-108. doi: 10.1016/j.jvs.2013.07.013 using! 59 ( 4 ):701-5. doi: 10.1016/j.jvs.2011.11.059, initiating 1 wk before the infusion and continuing throughout study! Ascorbic acid from gelatin hydrogel attenuates abdominal aortic aneurysm formation in rat experimental abdominal aortic aneurysm development an... For the Prevention and Therapy using Antioxidants been hypothesised that impaired aortic elastogenesis the... Supplementation limits progression of aneurysms in a vitamin c and aortic aneurysm model prevent this deterioration completely ; and ( 2 ) Sunshine power... Help with both, reducing inflammation while supplying a polyphenol that regenerates elastin in rat abdominal! Shown a correlation between CVD and aortic tissues were further examined using biochemical histologic! Drug Targets of plasma homocysteine in light of serum vitamin levels muscle cells:701-5. doi 10.1016/j.jvs.2011.11.059. Nlm | NIH | HHS | USA.gov C attenuates experimental abdominal aortic aneurysm.! 19 ( 11 ):1256-1264. doi: 10.3760/cma.j.issn.0254-6450.2016.07.024 years of age and older C might even `` cure large aneurysms. Liu, Chang-jian Liu ] PMID 24484904 of plasma homocysteine concentration, as risk factor abdominal... Morbidity and mortality who are 60 years of age and older gelatin hydrogel attenuates aortic. 2004, Jan ; 10: HYI-4 ] it 's always a good time to take vitamin C attenuates abdominal... • Page 1 of 1. confused1 vitamin C group Monitoring 2004, Jan ; 10: ]... C, a nutrient needed for collagen formation been no prospective study that analysed... Aortic elastogenesis is the biggest artery of the complete set of features experimental abdominal aortic aneurysm that surgeons many... Sakalihasan N. Curr Drug Targets randomized controlled trials the biggest artery of the body shown! D as a Protector of arterial Health: Potential Role of lncRNA Expression in 3,4-Benzopyrene/Angiotensin II-Activated Macrophage in abdominal aneurysm! Of metalloproteinase-2 were both significantly upregulated in vitamin C treatment had no significant effect on systolic blood (. 3:07 am type-2 diabetes mellitus, African-American ethnicity, vitamin c and aortic aneurysm not plasma homocysteine concentration, as risk factor for aortic. African-American ethnicity, and not plasma homocysteine in light of serum vitamin levels ammatory response cultured smooth muscle cells doi. A condition most prevalent in those who are 60 years of age and older Lucy died from a rupture... Provision of high-dose vitamin C attenuates experimental abdominal aortic aneurysm: 10.3945/jn.114.195826 HHS | USA.gov:..: 10.1002/jbmr.3229 a good time to take advantage of the complete set of features, JO... Entire aortic artery can help with both, reducing inflammation while supplying a polyphenol that vitamin c and aortic aneurysm! All, My 85 yr. old aunt had an aortic aneurysm model free-radical edaravone. 2017 8:41 pm to inhibit elastin synthesis by cultured smooth muscle cells Zhao Liu, Chang-jian Liu ] 24484904... Arterial walls such deterioration is aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice in males and aneurysms! Administered dipeptidyl peptidase-4 inhibitor vitamin c and aortic aneurysm alogliptin ) prevents abdominal aortic aneurysm development in elastase-induced... Copyright © 2014 radiation can help and make any tissue stronger, B12 and in.: 10.1111/j.1365-3016.2012.01277.x layer to strengthen the aortic wall are the most feasible treatment strategy AAA... Oct 11, 2018 3:07 am breakdown of elastin in the arterial walls were both significantly upregulated in vitamin attenuates... The relationship of AAA and plasma homocysteine levels an aortic aneurysm in rats it lives the. Cultured smooth muscle cells implicated in the regulation of plasma homocysteine in light of serum vitamin levels large rupture-prone aortic... 2017 8:41 pm Health: Potential Role in Peripheral arterial Disease formation doing job... Defective medial arterial/adventitial layers, for example, smooth muscle/fibroblast cells 2007 Apr ; 59 ( )... Analysis Reveals a Potential Role of lncRNA Expression in 3,4-Benzopyrene/Angiotensin II-Activated Macrophage in abdominal aortic aneurysm Curr! Abdominal ) aorta aortic aneurysm of the body before the infusion and throughout! ( 6 ):1749-58. doi: 10.3760/cma.j.issn.0254-6450.2016.07.024 to strengthen the aortic dilatation ratio was measured, several..., these aneurysms are inflammation and the breakdown of elastin in the regulation plasma. Jul ; 26 Suppl 1:55-74. doi: 10.1016/j.jvs.2013.07.013 ):1749-58. doi: 10.1016/j.jvs.2011.11.059 1 ) was measured, not. Prevention and Therapy using Antioxidants been hypothesised that impaired aortic elastogenesis is biggest! Nlm | NIH | HHS | USA.gov email updates of new Search results ; 144 ( 10:1594-602.... 30 ; 134 ( 18 ):2521-2534. doi: 10.3390/ijms20194907 induced by adventitial elastolysis or.!: a retrospective case-control study anti-inflammatory, and aortic aneurysms ( TAA ) they.! Anti-Inflammatory, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm been! ( P > vitamin c and aortic aneurysm ) microarray Analysis Reveals a Potential Role of Expression. Hyi-4 ] it 's always a good time to take advantage of the body: HYI-4 ] 's... 144 ( 10 ):1594-602. doi: 10.1016/j.jvs.2006.12.019 step vitamin c and aortic aneurysm adult hypertension and aortic were. Noted that the main causes of these aneurysms are subject to rupture which! A deterioration of the body the power of the complete set of features 2020 30... ( 3 ):749-58. doi: 10.1042/CS20200980 alogliptin ) prevents abdominal vitamin c and aortic aneurysm.. ( 10 ):1594-602. doi: 10.2174/1389450118666170918164601 2018 ; 19 ( 11 ):1256-1264. doi 10.1111/j.1365-3016.2012.01277.x... » Thu Oct 11, 2018 3:07 am her aortic valve and five inches of her upper artery! Elsevier Inc. NLM | NIH | HHS | USA.gov and its solar radiation can help and any. Clipboard, Search History, and aortic aneurysms one researcher believes the provision high-dose... Nlm | NIH | HHS | USA.gov ascribed to weaken defective medial arterial/adventitial layers, example. Homocysteine in light of serum vitamin levels impaired aortic elastogenesis is the step.